The Challenge of Skin Lesions in Systemic Diseases

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Ana Isabel Lopes - Corresponding Author

Ana Isabel Lopes []
Rua Dr. Eduardo Torres, 4464-513 Senhora da Hora, Matosinhos, Portugal
ORCID iD: 0000-0002-0043-8833

Isabel O. Cruz
Rui Môço


A 47-year-old man, obese, without medical problems, presented with a 15-day history of painful erythematous nodular lesions on the anterior side of lower limbs. He had no improvement with antibiotics and non-steroidal anti-inflammatory drugs (NSAIDs). He developed migratory and symmetric arthralgias (ankles, knees, elbows) and low-grade fever. The skin lesions progressed to the upper limbs. On physical examination, a mild swelling and tenderness in both ankles was noted, and lesions suggestive of erythema nodosum were seen.[...]

Keywords: Erythema Nodosum; Sarcoidosis

Article Details

Lopes AI, O. Cruz I, Môço R. The Challenge of Skin Lesions in Systemic Diseases. Gaz Med [Internet]. 2021 Jun. 30 [cited 2023 Sep. 27];8(2). Available from: