Schnitzler Syndrome: A Clinical Entity to be Considered in Patients with Chronic Urticaria Síndrome de Schnitzler: Entidade Clínica a ser Considerada em Doentes com Urticária Crónica

Main Article Content

Ana Catarina Carvoeiro - Corresponding Author

Largo Águias Serpa Pinto, Lote A, 4740 Fão, Esposende, Portugal

 

Sérgio Silva
António Sampaio
Alberto Leite
Mariana Couto
Paulo Bettencourt

Abstract

INTRODUCTION: The charring of rare clinical conditions where the clinicians can significantly change patients’ management is relevant, it alerts to its recognition and permit to share knowledge with potential clinical impact.
CASE REPORT: We present a 32-year-old male that has been previously evaluated in Dermatology and Immunoalergology appointments due to chronic urticaria. He had urticarial rash for eight years. He complained of asthenia and arthralgia. He has been on anti-histaminics and posteriorly cyclosporine has been added without complete resolution of symptoms. He has been referred to Internal Medicine appointment due to elevated sedimentation velocity rate (65 mm). In the diagnostic study, an IgM/K monoclonal gammopathy was identified. Schnitzler syndrome was diagnosed and the patient began with colchicine with total resolution of symptoms.
DISCUSSION: Schnitzler syndrome is a rare condition with a still not completely understood physiopathology. It has been known as an auto-inflammatory condition. Schnitzler syndrome diagnosis requires high suspicion, so descriptions as ours are important to give notoriety to this condition.


Received: 13/04/2017 - Accepted: 24/11/2017

Keywords: Schnitzler Syndrome; Urticaria

Article Details

1.
Carvoeiro AC, Silva S, Sampaio A, Leite A, Couto M, Bettencourt P. Schnitzler Syndrome: A Clinical Entity to be Considered in Patients with Chronic Urticaria: Síndrome de Schnitzler: Entidade Clínica a ser Considerada em Doentes com Urticária Crónica. Gaz Med [Internet]. 2018 Feb. 21 [cited 2022 Aug. 13];4(4). Available from: https://www.gazetamedica.pt/index.php/gazeta/article/view/86
Section
CLINICAL CASE

Most read articles by the same author(s)