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Chromophobe renal cell carcinoma is a rare histological entity of renal cell carcinoma. An unusual clinical case presentation is described in a 50-year-old man, asymptomatic - a giant right renal mass (224 x 180 mm) with no associated secondary lesions.
The patient had no symptoms, such as low back or abdominal pain or even hematuria. His unique complain was a slight increase in the abdominal volume. This finding was done by ultrasonography on routine exams. The presumptive computed tomography diagnosis was primary renal tumor. A right radical nephrectomy was made without perioperative complications.
The histological finding was a chromophobe variant of renal cell carcinoma.
Despite the dimensions of the lesion, there are cases including the current one, which have a favorable evolution and where the indication for radical nephrectomy is the first option.